Torque Ketomac shampoo

Torque Ketomac shampoo

Torque Ketomac shampoo treatment shampoo contains Ketoconazole, a broad-spectrum synthetic antifungal agent in a concentration of 2% in an aqueous suspension.

Torque Ketomac shampoo is basically a formulation of, Ketoconazole, which is a used for topical application, as a broad-spectrum synthetic antifungal agent in a concentration of 2% in a shampoo/cream base.
Ketoconazole is an azole antifungal that works by preventing the growth of fungus. It is in the same family of drugs as fluconazole, itraconazole, and miconazole. Ketoconazole works by preventing the formation of fungal cell walls, thereby stopping fungal growth.
Ketoconazole is (±)-cis-1-Acetyl-4-[p-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine and has the following structural formula:

HOW DOES Torque Ketomac shampoo WORK?

Torque Ketomac shampoo contains Ketoconazole that kills fungi and yeasts by interfering with their cell membranes. It works by preventing the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol disrupts the fungal cell membrane, thereby weakening it. The weakened cell membrane allows the contents of the fungal cell to leak out resulting in its death. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As ketoconazole causes holes to appear in the cell membranes, essential constituents of the fungal cells leak out. This kills the fungi and thereby treats the infection. Ketoconazole works by killing fungi on the skin called Malassezia.

WHAT IS Torque Ketomac shampoo USED FOR?

Torque Ketomac shampoo

It is used for the prevention and treatment of dandruff. It treats flaking, scaling, itching, dandruff and also helps to relieve inflammation due to dandruff. Topical ketoconazole is used for treating ringworm, jock itch, athlete's foot, dandruff, and tinea versicolor.

DANDRUFF:

Dandruff is a form of skin eczema called seborrhea. Scalp seborrhea and dandruff do not cause permanent hair loss. Often, scalp seborrhea doesn't even itch significantly. Dandruff scale is a cluster of corneocytes, which have retained a large degree of cohesion with one another and detach as such from the surface of the stratum corneum. A corneocyte is a protein complex that is made of tiny threads of keratin in an organized matrix. The size and abundance of scales are heterogeneous from one site to another and over time. Parakeratotic cells often make up part of dandruff. Their numbers are related to the severity of the clinical manifestations, which may also be influenced by seborrhea. A number of antifungal treatments have been found to be effective including ketoconazole, zinc pyrithione, and selenium sulfide. Ketoconazole as a shampoo appears to be the most effective.

TINEA (PITYRIASIS) VERSICOLOR:

Tinea (pityriasis) versicolor is a non-contagious infection of the skin caused by Pityrosporum Ovale. This commensal organism is part of the normal skin flora. In susceptible individuals, the condition is often recurrent and may give rise to hyperpigmented or hypopigmented patches on the trunk which may extend to the neck, arms and upper thighs. Treatment of the infection may not immediately result in restoration of pigment to the affected sites. Normalization of pigment following successful therapy is variable and may take months, depending on individual skin type and incidental skin exposure. The rate of recurrence of infection is variable. An exaggerated use washing test on the sensitive antecubital skin of 10 subjects twice daily for five consecutive days showed that the irritancy potential of KETOMAC Shampoo 2% was significantly less than that of 2.5% selenium sulfide shampoo.

MECHANISM OF ACTION:

Ketoconazole works by killing fungi on the skin called Malassezia. These fungi occur naturally on the skin, however, people suffering from dandruff seem to have more of Malassezia. It works by interfering with the synthesis of ergosterol, a vital component of fungal cell membranes, thereby weakening it. The weakened cell membrane allows the contents of the fungal cell to leak out resulting in its death.

INDICATIONS of Torque Ketomac shampoo:

Ketomac Dandruff Treatment Shampoo is used for the prevention and treatment of dandruff. It treats flaking, scaling, itching, dandruff and also helps to relieve inflammation due to dandruff. It may also be used for other conditions as determined by your physician.

CONTRAINDICATIONS of Torque Ketomac shampoo:

Contraindicated in people who are hypersensitive to the active ingredient or any of the excipients in this formulation.

PRECAUTIONS of Torque Ketomac shampoo:

The shampoo may be irritating to mucous membranes of the eyes and contact with the eyes should be avoided. If the shampoo gets into your eyes, rinse them gently with clean water.
If a sensitive reaction or chemical irritation occurs, use of the medication should be discontinued and consult physician.

DIRECTIONS FOR USE:

KETOMAC SHAMPOO

Wet hair and scalp thoroughly. Apply a small amount of KETOMAC Shampoo to your scalp and massage into a lather. Leave it on for 5 to 10 minutes and then rinse your scalp thoroughly. Use twice a week for 4 weeks. After the scalp has cleared, use KETOMAC Shampoo once a week to prevent the reoccurrence of dandruff and to keep the scalp clear. If you stop using KETOMAC Shampoo completely, your symptoms may reappear.

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